hydrophobic pocket

hydrophobic pocket
hydrophobic pocket,
a water-repellant, pocketlike fold on the surface of a protein that repels water and affects the protein's shape: »

One leading idea is that anaesthetics bind to proteins at sites called hydrophobic pockets (New York Times).


Useful english dictionary. 2012.

Игры ⚽ Поможем сделать НИР

Look at other dictionaries:

  • Bcr-Abl tyrosine-kinase inhibitor — Bcr Abl tyrosine kinase inhibitors (TKI) are the first line therapy for most patients with chronic myelogenous leukemia (CML). In more than 90% cases CML is caused by chromosomal abnormality resulting in the formation of a so called Philadelphia… …   Wikipedia

  • Discovery and development of non-nucleoside reverse-transcriptase inhibitors — Non nucleoside reverse transcriptase inhibitors (NNRTIs) are antiretroviral drugs used in the treatment of human immunodeficiency virus (HIV). NNRTIs inhibit reverse transcriptase (RT), an enzyme that controls the replication of the genetic… …   Wikipedia

  • Discovery and development of small molecule c-Met inhibitors — The c Met (mesenchymal epithelial transition) tyrosine kinase stimulates cell scattering, invasion, protection from apoptosis and angiogenesis.[1] c Met is a receptor tyrosine kinase,[2] which can cause a wide variety of different cancers, such… …   Wikipedia

  • Cerastocytin — Cerastocytin: Thrombin like serine protease in snake venom. Contents 1 Function Overview 2 Structural Comparison to Thrombin 2.1 Hydrophobic pocket. 2.2 Positive Surface …   Wikipedia

  • PDE1 — (phosphodiesterase1) is a phosphodiesterase enzyme also known as calcium and calmodulin dependent phosphodiesterase. It is one of the 11 families of phosphodiesterase (PDE1 PDE11). PDE1 has three subtypes, PDE1A, PDE1B and PDE1C which divide… …   Wikipedia

  • PDE3 — phosphodiesterase 3A, cGMP inhibited Identifiers Symbol PDE3A Entrez 5139 HUGO …   Wikipedia

  • CCR5 receptor antagonists — are a class of small molecules that antagonize the CCR5 receptor. The C C motif chemokine receptor CCR5 is involved in the HIV entry process. Hence antagonists of this receptor have potential therapeutic applications in the treatment of HIV… …   Wikipedia

  • Theories of general anaesthetic action — Structures of general anaesthetics widely used in medicine. A general anaesthetic (or anesthetic) is a drug that brings about a reversible loss of consciousness. These drugs are generally administered by an anaesthetist/anaesthesiologist in order …   Wikipedia

  • Outdated theories of anaesthetic action — See the general anaesthetic page for current theories. A general anaesthetic (or anesthetic) drug is an anaesthetic drug that brings about a reversible loss of consciousness. These drugs are generally administered by an… …   Wikipedia

  • Discovery and development of integrase inhibitors — The first human immunodeficiency virus (HIV) case was reported in the 1980s. Many drugs have been discovered to treat the disease but mutations in the virus and resistance to the drugs make development difficult. Integrase is a viral enzyme that… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”